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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e293dd7dc59b9cbcd21a45e9b4b19102a79724060c29bf9b78984e2d391571a' 
  AND token = 'zngFVPb2PaOW2GTg7yjEMw+x0W1AJqx3vQEO3ioP3L0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}