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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b54958c189f3430bd27b68c42bf9f578692e82cf818717b956b65f042abb355' 
  AND token = 'iv/2ki7tOLFrQqJ8VCrprQI59upKMVV5vtl0avMM2Sc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}