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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b46d60305a68685e14439e07147bb73646fdc99dc24d1fc58b3543eeafdce195' 
  AND token = 'xj5NMUvSdY0khvgjKddTC2LAdXQSNs5H9L+bwVg5L50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}