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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef484174779ba89fe4364d6363c221a66d6bb8df3f162b5139e52e2c6d5fbf4c' 
  AND token = 'y8ZMORSyE/TMhkp+P68W6Y79zX9a5gR4ErpjN6DZGWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}