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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbd3e3d7105e1ad83d3a1488da6aa835133543fd1af1ce730fb9bc0865a0ad46' 
  AND token = 'YIWanLOuws28F1/+y/aWGW/opgzpSY/s+r28NK9thHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}