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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00f1622cc7de2384e7a9d35c87f86aa63a8b6fe5aa50884b04877ec9224dac82' 
  AND token = 'xOkgebrPPqvjpMB6/WsQ6ibDOuL2PcTDwI61msBxoF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}