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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e43f27af267f1c1bc9c8bef9a08220f9eb4c08be2507d56e0c95b8d8478b44c3' 
  AND token = 'FXQNm+glxkda0cyo4ZJwTTpMVqDIaRfWzqWUpizp3OQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}