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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0a7d0a0f3d628f6135ce1c443344a969a0e212f3aa1c5f200b592dba38215a1' 
  AND token = 'J36sGoxdHDZ/AJL/Fx9en+PnCmMD+IP1Q4kQ3qIq91c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}