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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4de1f7d05baa37e61900b1be0baa4e7d6c9c862a5577617eb4e645666f21c54' 
  AND token = 'mrwZn8H6FF6jshGCgc3nxUiaPP67VhsyjbuwF3eS4io=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}