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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9422afe11bbd6795cfaf8697e776d0c49b0eadfe85ef9f0a4cd638b9f431ce88' 
  AND token = 'lB6MmA8puZXmmHs/JXRBTjd4s/MdX4OPr0MCss3JOFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}