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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd16c0a8be61b99f62b98bb0f61a1d2eead548244e45261b0c21dc7380c7dce8f' 
  AND token = 'F40Qn3PJvizt1u4C/56Jk1w46pL1oE1Hz74ywj4T+Ww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}