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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa085a5e1e952ba376f4766fb60858a10dd0b99a5d286890e929c58f2156fdb2' 
  AND token = 'KPWM5Q2ISXboy+3Jr06X0IAxP4hIKhP9sgFlF3d4Nrs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}