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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa2aade5e0b122a982a57cc507b09df69765eb00a25a11ac964f05446ba77bb0' 
  AND token = 'Yp3JKTkT3X16mkMW4sRg+rSn39ndoDYvXgK9C4/+7ro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}