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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54e0f15ea4fd07be8bbd8aefdca668e9fbe44172e62b733c97610ad2a21e095e' 
  AND token = 'wOy37kk0iXZeKGYpEGU0GSn6YjuF2l6lmhREN0zQEZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}