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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea79f9028d44fe459d691b921cea51a68f1f118d7205b9104dcb68d2724d134f' 
  AND token = 'JE5LyluXmkyotFAfDZfmPR67nT8y2uouMAGel+v5NxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}