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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '636b5058ebf074bd59dbe493ffe76070ee7f5335f49f4a16459ff9061253175d' 
  AND token = 'OMy8WAz+ZY3DI2y/xT20zVaXmOLYt6V3OAi+pvZay9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}