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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb85a9ee21828bb0b478adba7d67fe5b84663dc451b3debde48963b480e6f84a' 
  AND token = '8HfjK3Xh24yuC/RFUeJfTu4EU6vHPH8GkTpB9KBIW3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}