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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c279cc475fd9fb22ed7292165d0e46136d2370da98031ebc01573f622b92503c' 
  AND token = 'N2ntu0Z0M6MXaBQLMpSEiHrPjrjpklg8S4VMEuDaauU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}