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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2b9a7038fe9ea5b01b4d74f87435e0d3dc6f04500700aab445d21f38b7fd68c' 
  AND token = 'nzgQSymDk1xMq1J/XinI5OA1PQzNn3uHmQ59+xK+KNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}