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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49ebe8422df911c09cf8780f77233fc835089bccf8814a9618d76f5df9427c77' 
  AND token = 'o+2diGdkGHeNU+Sg0lsVr9+HGN6S4V06Yyfx9Vzhvtw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}