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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de7c3b9be01a4accc19839b33e05d8a50c60366403a4730dc9008d7a6abb2433' 
  AND token = 'FL+2B6wEnteV7DAdV4yT7OQQDpmXKCB6rdmQjqRbIxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}