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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8e44d3bc687843f46dfe53815c3e78e64f887492f7a9b1d2b1b299f13739d77' 
  AND token = 'ibqes4w/EM6a31o7KTix+Y8uYTxhcVWuxsoq9Z7VM+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}