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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88016bc41fb4d34ad460cbe46ded0036c4f9207cc8dd72cbce07b8f2b5df87ca' 
  AND token = 'EGGF1Jh0id+kMXjEvXqeBxQNT26bo5c+qsm8xVQ6OPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}