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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1172377b14878c85c0184764c2402488062957738df2eb021ad2e592a8813948' 
  AND token = 'AuB0ywhnU3hYE8bX1cukPZQk/zQHjApwOF8ZfLv4eyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}