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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06f7b8d40f134df5ea6b536f81fc1496d4eb9a888dafa935b254045f0f52d5c6' 
  AND token = 'dYD4mOSJkJaOBQjBXH2P3Bh3FvrejFtUBjWF6ncRrrc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}