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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a7260ffd50e8c0b6629911045f7df14eb4d72ee26e1a40fef37abffdcea079d' 
  AND token = 'gug/5D2tA9LnuG2acsoJAY+iIx0kiDbRETzpPNhVe3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}