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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3686c7d7e0e69541a8e99797efd79ad85658dd9826361ed07c8e9eb0d5cc7f69' 
  AND token = 'liEtRoXabPqiRouBUR6wcp/9VlorVPRWb2bxAuDpO1o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}