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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37e7cb0ad2ef3f05e605edacaa9d0cb86e7f73e9f30f6e4dcf60454744155991' 
  AND token = 'XzypVcI5lQc/AIGnB2FWTScDor+zYJNCTq2ioWUtR8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}