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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53130920c2ac76919865a283bddf677e840180c5c46d34da5730e67ecee2738c' 
  AND token = '+0t8ZFO9Jbh9ezt8Mg7K2QLd7l6nP6V46r3tUI+LOuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}