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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52ed32178df9c224eb2a49e28271a8918733f93d54d33711e62e7c972af374f9' 
  AND token = 'IeeViN38OOKItUjIB3zVK74QTZ7N5954qtnt7AzYsgQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}