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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e66d71c2dbaaabc7c5cdfceb2e6578152ba6b3acd3c282e2b82851964f099dd7' 
  AND token = 'hVSqT2QiO078TDF/wFDUIV9in/MfGGLiRcCapyewhRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}