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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '545675b2d0921d13aece37882706204a4487119e9ae58dcd44265814663d0232' 
  AND token = 'y5ROHW7l/aYdtb9jVcDp7JOb3mFt8k1y6nd6Iqt+/L8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}