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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a035592c2d5b6d7de5b85c80fe275c86ed8be4a9ffef9e417eb7eda8bc436094' 
  AND token = 'Ei8RyGnkLTNET6sdtgT/zJA/emOPk/kn/j+Zj8aSOdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}