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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99d09b0a6b6e1bf26d66b4c9d0666b8b045dd380a8303200d65b8c651dfbc387' 
  AND token = 'xss3R8iRcVB7dpRW7ui2G+qK1Cly/lgQKVjTTwmQVZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}