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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f33384b5a4734e8a5eb40d4feb9a4e996350506f6510033aaf3a4ff9efe1f4f3' 
  AND token = '+ysm3SCmQCC3Vbtl53VRyM91Zl3zbXCFgopvkKlh7Uo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}