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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c0afb51383c67404c81f417778b5fef1d140113125e370679ebe42da9a6a04f' 
  AND token = 'jtW8VCFEW6UBSoXOfGv50Y3gbkAmpvV1PF10JvoG96Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}