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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b10dad8314e726e00f1a9ac8d3ba4bb85f08540ff9d2409a7e24cb6b5016058' 
  AND token = 'ms5yhhfE2vrwyBf5zZNyZzq/ra8S/rc/7Zyh24YC1Lc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}