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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6b6d6abce7ca1b14b576b26494b342cc649c3e9f16a96d0fdd222aac34bee65' 
  AND token = 'oGujLPCW6KG4N+zK1EVrZ/KQ5TttwEoIMLmiHx+j1ME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}