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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f453316fef349379dcd15a9224db2e569ca1ade2b2a2fa34d5d3fd612ec08a70' 
  AND token = 'jXAhGLGy8fB1Wv3kxizm+bjt9pdLf2VKZz3fI70+bQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}