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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c0567f102c9b116273c1be42f64fe88e84b73e2c2c7274eac6cfdb7bbaa5f1d' 
  AND token = 'q7DQmucx3KA86YG/YloK5OQ0o/edj62hCR5HfeT3Ovo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}