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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a42281a55b7357857d39f35a84a90eb9b61b99bb619cc720d029a6b785b00f9' 
  AND token = '9nYev8KaX7JXbbVKtiERNaKVbV7IejMsceUCGMFtsD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}