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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1220156d078e2daa9afe8541de2a1c70fa46d89fe2b0d4bafb5d432fa2e5e205' 
  AND token = 'p+dSohj+QiLcqUmcyLEqHbDIGohs/6YV0iM0cP7iuVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}