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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '211745361222774e169e0677a837fba9a479799d9e3413332dc031e4bfb8cfa3' 
  AND token = 'pVKgprcu+/jozA9OkFUr+sWJ3JkkKBz6fjK8TP11Vks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}