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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b1ad81553edf3cbafd201504e8452339d1c6588e393e12520995374884499d2' 
  AND token = 'dMvxIpKYtOwktNafrJDRwMuOK5a3knQzBRv8nh+z178=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}