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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ca5c4bd9b56228c474270316381b4e9fbda0c4eea8a9b68e9a0218f8bc6c231' 
  AND token = 'bZd4BdQn5J3rD4sAMpwVimDcqrUORle4Q3Bl7VPsAaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}