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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74c80cf3cbe8b72d967d99d780d230427e16697f413e47aab41d3d1f08778e14' 
  AND token = 'uf8f7AJ2osaiGX0dZgPA4wEso5B6nSzE8ONWlhxlCCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}