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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cc53489d61f08be6d824302b8088b69cb31334c00d5b485efbec3c613c325fb' 
  AND token = 'grkiMsqt6TMuZLXwnFcMz6eItr7GGsEkHDI57LH3TDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}