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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0dae4f6d09edb6f5c5b8a47e5e604b39956462acc308ae5253a1d397a72144a' 
  AND token = 'Hk8fOboUBGbS/36kQTQncAdp1N5hzN6C6vzPhzBR8Qs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}