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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2308ebe55b5334c3ecb7b09f74a6eb5ab60cb5625ca3c325bc02d1706e715d5c' 
  AND token = 'wdW1A8lzjySMYVjM/8OKfFby7L1yL7bS4AvWckFEOQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}