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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73beaf50f18d742820e7d5c7ad4bac1983f81db719619879fc2e0facb47dac6c' 
  AND token = 'H/ssuA35xrqpdPAqoyDOdCLJyAyUrB7gS4aV3aYr8lM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}